I just got a position! Start date march 13th!

2021.10.26 06:29 Fuxitadventure I just got a position! Start date march 13th!

Man, I almost gave up on the whole wildland firefighting idea until yesterday. The hard work payed off I finally sunk a position on a engine module in New Mexico.
submitted by Fuxitadventure to Wildfire [link] [comments]


2021.10.26 06:29 svanapps r/cardano - How to track balance with 3rd part trackers?

submitted by svanapps to CryptoToFuture [link] [comments]


2021.10.26 06:29 Ricosss Pan-Cancer Analysis of Glycolytic and Ketone Bodies Metabolic Genes: Implications for Response to Ketogenic Dietary Therapy. (Pub Date: 2021)

https://doi.org/10.3389/fonc.2021.689068
https://pubmed.ncbi.nlm.nih.gov/34692477
Abstract Background
The Warburg effect, also termed "aerobic glycolysis", is one of the most remarkable and ubiquitous metabolic characteristics exhibited by cancer cells, representing a potential vulnerability that might be targeted for tumor therapy. Ketogenic diets (KDs), composed of high-fat, moderate-protein and low carbohydrates, are aimed at targeting the Warburg effect for cancer treatment, which have recently gained considerable attention. However, the efficiency of KDs was inconsistent, and the genotypic contribution is still largely unknown.
Methods
The bulk RNA-seq data from The Cancer Genome Atlas (TCGA), single cell RNA sequencing (scRNA-seq), and microarray data from Gene Expression Omnibus (GEO) and Cancer Cell Line Encyclopedia (CCLE) were collected. A joint analysis of glycolysis and ketone bodies metabolism (KBM) pathway was performed across over 10,000 tumor samples and nearly 1,000 cancer cell lines. A series of bioinformatic approaches were combined to identify a metabolic subtype that may predict the response to ketogenic dietary therapy (KDT). Mouse xenografts were established to validate the predictive utility of our subtypes in response to KDT.
Results
We first provided a system-level view of the expression pattern and prognosis of the signature genes from glycolysis and KBM pathway across 33 cancer types. Analysis by joint stratification of glycolysis and KBM revealed four metabolic subtypes, which correlated extensively but diversely with clinical outcomes across cancers. The glycolytic subtypes may be driven by TP53 mutations, whereas the KB-metabolic subtypes may be mediated by CTNNB1 (Ξ²-catenin) mutations. The glycolytic subtypes may have a better response to KDs compared to the other three subtypes. We preliminarily confirmed the idea by literature review and further performed a proof-of-concept experiment to validate the predictive value of the metabolic subtype in liver cancer xenografts.
Conclusions
Our findings identified a metabolic subtype based on glycolysis and KBM that may serve as a promising biomarker to predict the clinical outcomes and therapeutic responses to KDT.
submitted by Ricosss to ketoscience [link] [comments]


2021.10.26 06:29 lupoman999 how this token work??

in my etherscan my token value is 540 dollars but in my metamask is showing 950 dollars????
submitted by lupoman999 to luffy_inu [link] [comments]


2021.10.26 06:29 n294 phone bill

i just paid my phone bill a day late but i still don't have data is there a late charge?
submitted by n294 to MetroPCS [link] [comments]


2021.10.26 06:29 Wicked2707 Little fur baby cuddles <3

Little fur baby cuddles <3 submitted by Wicked2707 to cats [link] [comments]


2021.10.26 06:29 123_dave Strange vision in Infinity War

So after what we see in Loki, what did strange see in Infinity War? And if the avengers took the gems from the past, shouldn't the TVA intervene?
submitted by 123_dave to MarvelTheories [link] [comments]


2021.10.26 06:29 igshahil Anybody knows the name of this girl ?

submitted by igshahil to spartacus [link] [comments]


2021.10.26 06:29 SirEntityTheGreat Fear The Walking Dead | S7:E3 "Cindy Hawkins" | Reaction & Discussion!

submitted by SirEntityTheGreat to FearTheWalkingDead [link] [comments]


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submitted by Necessary-Eye-2249 to CryptoMars [link] [comments]


2021.10.26 06:29 recumbentrambler Walking the dog - another job for the recumbent trike

Our adult son is staying with us for a while. His dog needs walking, and as I ride every day on my Greenspeed Magnum, it fell to me to walk her. It turns out that a recumbent trike provides the best means to walk a large dog. I can sit back, relax and listen to an audiobook when she wants a long sniff, I can make her run for cardio, and we can do the distance she needs. So, I wrote a blog article about it. Let me know what you think.Recumbent Rambler Dog Walking Blog
submitted by recumbentrambler to recumbent [link] [comments]


2021.10.26 06:29 Ready-Common3069 Darkrai on me 0696 6063 1730

submitted by Ready-Common3069 to PokemonGoRaids [link] [comments]


2021.10.26 06:29 HowkinsW Anime_irl

submitted by HowkinsW to anime_irl [link] [comments]


2021.10.26 06:29 Pureenus My partner's requiring help but does not have a Medicare card nor any insurance. Where can I recommend her to in Sydney that's not too overpriced?

She's currently in need of psychiatrical help and would like to know if anyone has had experience in Sydney with this scenario?
submitted by Pureenus to sydney [link] [comments]


2021.10.26 06:29 NDHoangMinh Internet speed problem!!!

Recently i had alot of problems with my game, unlike any other game like ER:LC or PTFS run smoothly. Now my main question is does this happen for every1 or its just me. (its not high ping lag its huge lag spike. Dont tell me about the server region, i alway join by PF Hub.)
submitted by NDHoangMinh to PhantomForces [link] [comments]


2021.10.26 06:29 hacker_backup Welcome to Anon Reddit, this is (probably) the only place on reddit where you can comment and post without showing your username to other users. You can never be sure who made this post.

submitted by hacker_backup to SideProject [link] [comments]


2021.10.26 06:29 Electrical_Prune6545 Wow

Wow submitted by Electrical_Prune6545 to ShitLiberalsSay [link] [comments]


2021.10.26 06:29 ruditumprolakl Join

https://discord.com/invite/6ApBEcwfVU
submitted by ruditumprolakl to branlette [link] [comments]


2021.10.26 06:29 memrplus What is going on?

I recently found out that i had far cry 6 downloaded on the wrong disc so i uninstalled it from epic games and installed it again. I launched the game and i got instantly redirected to ubisoft connect and it's saying that i need to download it AGAIN. But it al ready downloaded a 50 gb far cry 6 from Epic. How do i fix this
submitted by memrplus to farcry [link] [comments]


2021.10.26 06:29 RLCD-Bot [Octane] [Tidal Stream] [Titanium White Synthwave] [Black Mandala: Infinite]

[Octane] [Tidal Stream] [Titanium White Synthwave] [Black Mandala: Infinite] submitted by RLCD-Bot to RLCustomDesigns [link] [comments]


2021.10.26 06:29 Many-Ad4736 Looking for manager

Good day Managers! I am looking for scholarship. Hard working and willing to dedicate my time playing axie everyday.
Name:Julius Garcia Age: 21 Gender: Male Location:Philippines Civil Status: Single Nationality: Filipino Device: AndroidPhone Connection: Mobile Data/Wifi Average SLP per day: 150-200
TELEGRAM:Julius Garcia
How many hours per day can you dedicate to playing Axie: I can play 8-10 hours a day.
Do you already have experience playing Axie Infinity: None, but i am willing to learn, research about Axie mechanics and to be educate and im a fast learner too.
Gaming Experience: Call Of Duty Mobile, Clash Of Clans, Mobile legends
Why should you hire me? - In this time of pandemic I'm looking for alternatives to help my family to support them in our financial needs and to pay bills while doing my passion of gaming I hope you'll give me a chance to be one of your scholars and I assure you that I will put my best and effort on it. Thank You!
submitted by Many-Ad4736 to AxieScholarshipsPH [link] [comments]


2021.10.26 06:29 Asgardus Folge der Spur von THE LΓ„ND

Folge der Spur von THE LΓ„ND submitted by Asgardus to stuttgart [link] [comments]


2021.10.26 06:29 ButterscotchDry6762 I do even knew this cat is green. Yeah he is green

submitted by ButterscotchDry6762 to WhatsWrongWithYourCat [link] [comments]


2021.10.26 06:29 l0st6666 Where am I?

Where am I? submitted by l0st6666 to backrooms [link] [comments]


2021.10.26 06:29 FlyingNetch ich_iel

submitted by FlyingNetch to ich_iel [link] [comments]


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